Tottenham Hotspur welcome Leeds United on Saturday evening in front of the live ITV cameras.
Leeds will once again be hoping to create the shock of the round after being the main giant killers in round three, when they disposed of Manchester United.
Spurs will be without former Leeds players Aaron Lennon and Jonathan Woodgate who both have groin injuries.
The home side will also be without Benoit Assou-Ekotto (groin), Carlo Cudicini (wrists and pelvis) and Tom Huddlestone (knee).
Leeds could still line up against two former employees, Danny Rose and Robbie Keane.
Leeds rested both Luciano Becchio and Patrick Kisnorbo in midweek and both will be expected to start.
Goalkeeper Shane Higgs (thigh) remains the only player on the sidelines for the visitors.
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