Leeds manager Kevin Blackwell will check on the fitness of Gylfi Einarsson and Dan Harding before naming his squad.
The pair both played as the reserves slumped to a 5-1 defeat to their Manchester United counterparts, and, provided they suffer no reaction to their injuries, could make the travelling party.
Harding will be particularly keen to face his former club, but Stephen Crainey stands by to deputise once again if he is ruled out.
Rob Hulse is pushing for a start after coming off the bench to score in the FA Cup draw at Wigan, but Blackwell may choose to keep faith with Robbie Blake and Richard Cresswell, who are forming a promising partnership in attack, while Michael Ricketts also played for the reserves after his loan spell at Cardiff ended.
Brighton boss Mark McGhee has no fresh injury worries for the clash with promotion-chasing Leeds.
Charlie Oatway, Alexis Nicolas, Jason Dodd and Chris McPhee are still on the injury list, however, while Adam Hinshelwood and Federico Turienzo got reserve run-outs in midweek, although they are some way from match fitness.
Michel Kuipers put in a fine performance for the second string and is pushing Florent Chaigneau for the goalkeeper’s jersey.
Teenage left-back Joel Lynch, who made an impressive debut against Southampton a fortnight ago, was cup-tied last weekend but will be available to face Kevin Blackwell’s side.
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